The research group of Professor Kenji Kabashima of Kyoto University Graduate School of Medicine and others is developing an atopic dermatitis therapeutic drug that is effective in suppressing itching with Kyushu University, Tokyo Teishin Hospital, Germany, research institutions in the United States, etc. Confirmed in a joint clinical trial.It seems to be good news for establishing new treatment methods.

 According to Kyoto University, the research group administers a therapeutic drug under development to 264 patients with moderate to severe atopic dermatitis in Japan and overseas, and is said to be involved in the development of itch. Interleukin-31 (* 1) ) The effect and safety on the receptor were verified.As a result, its usefulness for itching was confirmed, but no serious side effects were observed.

 Patients with atopic dermatitis take longer to fall asleep due to itching and may wake up in the middle of the night.For this reason, the research group believes that the treatment under development is also effective for insomnia.

 Atopic dermatitis is a skin disease whose main symptoms are itching and eczema.It has been chronically aggravated and recovered, and has a great impact on the lives of patients and their families.Professor Kabashima said, "It was reconfirmed that interleukin-31 is deeply involved in itching because this therapeutic drug suppressed itching. Control of interleukin-31 is a great help as a therapeutic means for atopic dermatitis. I think it will be. "
(* 1) Interleukin-31 A substance that causes itching in atopic dermatitis and is mainly produced by helper T cells.

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