A research team led by Assistant Professor Takeshi Inoue and Assistant Professor Chihiro Morishita of Tokyo Medical University conducted a case-control study of inpatients and evaluated the relationship between the use of psychotropic drugs and the occurrence of falls.As a result, it was shown that the use of sleeping pills is a risk factor for falls, and it was suggested that refraining from prescribing sleeping pills as much as possible may lead to a reduction in the incidence of falls.

 Falling / falling of inpatients is a frequent accident, and it is important to accurately evaluate the risk and to use drugs that can increase the risk carefully.It is said that psychotropic drug use may increase the risk of falls due to its mechanism of action, but the relationship between psychotropic drug use and the occurrence of falls / falls has not been clearly evaluated so far. rice field.

 The research team decided to use "a design that evaluates only new users of psychotropic drugs" using reliable data collected from medical records.A case-control study was conducted on inpatients at Tokyo Medical University Hospital, with 2016 people who fell or fell in 254 as a case group and 254 non-falls who were hospitalized during the same period as a control group.Evaluate the relationship between the use of psychotropic drugs (antipsychotics, antidepressants, anxiolytics, sleeping pills) and the occurrence of falls / falls, and determine whether the use of psychotropic drugs in each class is a risk factor for falls / falls. investigated.

 As a result, the relationship between the use of antipsychotics / antidepressants / antidepressants and the occurrence of falls / falls was not statistically significant, but the relationship between the use of sleeping pills and the occurrence of falls / falls was statistically significant. It was suggested that the use of sleeping pills is a risk factor for falls.

 In the future, we would like to increase the number of study subjects, evaluate the relationship between the use of individual drugs and the occurrence of falls / falls, and examine which drug use is a risk factor for falls / falls.

Paper information:[Psychiatry and Clinical Neurosciences] Psychotropics use and occurrence of falls in hospitalized patients: A matched case-control study

Tokyo Medical University

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