Tohoku University Tohoku Medical Megabank Organization (ToMMo) conducted antibody tests for the new coronavirus on about 3,000 people in Miyagi prefecture, and almost all of them were antibody-positive in the antibody tests from the month following the second vaccination with the new coronavirus vaccine. was.

 同機構は2013年より東日本大震災の心身への影響を把握・分析し、地域の保健・医療の向上を目指して長期健康調査を開始。2021年7月から11月に、3回目の追跡調査の項目の一つとして、3,008人(27~94歳、平均65.0歳)に新型コロナウイルス(SARS-CoV-2)の抗体検査を行った。

 Antibodies are proteins called immunoglobulins that work to eliminate foreign substances such as pathogens from the body.Of these, antibodies that bind to the virus and have the effect of inhibiting the intracellular invasion of the virus are called "neutralizing antibodies."Although the study measured the total amount of antibody rather than neutralizing antibody, a link between the amount of antibody measured by antibody testing and the amount of neutralizing antibody is suggested in many cases.

 As a result of the antibody test analysis, all but 2 out of 2,168 double-dose vaccinations of the new coronavirus vaccine were positive, indicating a sufficient increase in antibody level.After a certain period of time after vaccination, the antibody positive rate was maintained, but the antibody level tended to decrease, and about 1 months after the second vaccination, the antibody level was about half.In addition, being female was associated with a high amount of antibody, and old age, drinking, and smoking were associated with a low amount of antibody.

 With this test, it is unclear whether the cause of the increase in antibody levels is a vaccine or an infection.However, this is the only survey in Japan that investigated the relationship between the number of vaccinations and the amount of antibody on a scale of several thousand people. It is expected that the effect and sustainability will be elucidated.

reference:[Tohoku University] Antibody production by the new coronavirus vaccine-From a survey of about 3 people from the Tohoku Medical Megabank Organization Cohort Survey- (PDF)

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