A research group led by a visiting researcher at the Graduate School of Medicine, Kyoto University, surveyed more than 7,000 people, the largest in the world, in the "Nagahama Cohort" project.Short sleep is associated with sleep apnea (sleep apnea), but hypertension / diabetes is associated with obesity and sleep apnea rather than short sleep, with gender differences and pre- and post-menopausal associations. It turns out that there is a difference.

 The Nagahama Cohort Project is a joint project between Kyoto University and Nagahama City, Shiga Prefecture, and conducts various tests for the purpose of promoting the health of citizens and cutting-edge medical research.In this project, the research group measured the degree of sleep apnea disorder and objective sleep time using a sleep diary and an accelerometer, which was not a subjective evaluation by a conventional questionnaire.Of the 9,850 project participants, 7.051 (71.6%) for whom measurement data could be obtained were analyzed.

 As a result, it was found that sleep apnea disorder is associated with objective short sleep.In addition, sleep apnea was associated with hypertension in both men and women, and became more relevant as the severity increased, but the association between sleep apnea and diabetes was found only in women, especially in premenopausal women. Diabetes mellitus increased 28-fold with moderate or higher sleep apnea.

 Obesity was associated with hypertension and diabetes in both men and women, but objectively measured short-term sleep was not associated with hypertension or diabetes.Furthermore, the involvement of obesity in hypertension and diabetes was indirectly mediated by about 20% due to sleep apnea, and gender differences were observed.

 This study is a cross-sectional study, and by continuing the current survey in the future, we will analyze the original degree of sleep time and sleep apnea disorders, or the effects of those changes on hypertension and diabetes, and discuss the causal relationship. It is said that it will be considered.

Paper information:[Sleep] Impact of sleep characteristics and obesity on diabetes and hypertension across genders and menopausal status: the Nagahama study

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