2023/9/5
Azabu University and Euglena confirm the ability of Yaeyama Chlorella to excrete mycotoxins that are toxic to the human body
Associate Professor Tomoki Fukuyama of the Faculty of Veterinary Medicine, Azabu University and euglena Co., Ltd. revealed that consumption of "Yaeyama Chlorella" produced by Yaeyama Shokusan Co., Ltd. of the Euglena Group promotes the release of "mycotoxins" that are harmful to human health. made it
Mycotoxins are chemical substances produced by plant pathogenic fungi and molds that contaminate stored grains, etc. Eating food contaminated with mycotoxins has a negative impact on the health of humans and livestock.For example, deoxynivalenol, a type of mycotoxin, causes loss of appetite and immunotoxicity, and ochratoxin A is a causative agent of nephrotoxicity and kidney cancer.If multiple mycotoxins cause complex contamination, there is a risk of synergistic toxic effects, and the challenge is to find materials that inhibit mycotoxin detoxification or absorption.
Previous research has shown that chlorella, a type of microalgae, has the ability to inhibit the absorption of aflatoxin, a type of mycotoxin.Therefore, this research group verified whether ingestion of Yaeyama macrolera has a toxin elimination effect on deoxynivalenol and ochratoxin A.
As a result, it was found that plasma and urinary mycotoxin levels were significantly decreased in mice ingesting deoxynivalenol and ochratoxin A mixed with Yaeyama chlorella compared to mice not mixed with Yaeyama chlorella.This suggests the possibility that Yaeyama chlorella is effective in inhibiting absorption of deoxynivalenol and ochratoxin A.
Next, Yaeyama macrolera, deoxynivalenol, and ochratoxin A were mixed in a test tube, centrifuged, and the mycotoxin concentration in the supernatant was examined. As a result, the mycotoxin concentration in the supernatant was found to be significantly reduced by mixing Yaeyama macrolera. .In other words, Yaeyama macrolera is thought to have the effect of strongly binding to deoxynivalenol and ochratoxin A, thereby inhibiting their absorption and promoting mycotoxin excretion.
Now that the usefulness of Yaeyama macrolera against mycotoxins has been revealed, further elucidation of the functionality of Yaeyama macrolera is expected in the future.