A research group led by Professor Hiroaki Oda of the Graduate School of Bioagricultural Sciences, Nagoya University has said that the reason why people gain weight when they skip breakfast is that they cause abnormalities in liver clock genes, lipid metabolism, and body temperature rhythm. It became clear in.

 The research group selected rats as experimental animals and divided them into a group that feeds a high-fat diet as soon as it enters the active phase and a group that feeds it with a delay of 4 hours, just like a human skips breakfast, and investigates changes in body weight, etc. rice field.

 They found that the group given 4 hours later gained more weight and heavier adipose tissue.At this time, the expression rhythm of the clock gene of the liver and the gene of the lipid synthesis system was delayed by 4 hours, and the body temperature did not rise until the meal was started.
Body temperature decreased during the rest period, but the group fed a high-fat diet with a delay of 4 hours showed a decrease in body temperature even though they were still eating.For this reason, the time during which the body temperature was rising was shorter than that in the group fed a high-fat diet as soon as the active period began.
The research group believes that skipping breakfast caused a shift in the body clock such as the liver, and shortened the active period to reduce energy consumption, resulting in weight gain.

 Although many reports have been made that breakfast is good for health, the genetic mechanism that occurs in the body has not been clarified.The research group reiterated that breakfast was the most important diet for normalizing the body clock.

Paper information:[PLOS ONE] Delayed first active-phase meal, a breakfast-skipping model, led to increased body weight and pertaining the circadian oscillation of the hepatic clock and lipid metabolism-related genes in rats fed a high-fat diet

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