Through collaborative research, Associate Professor Tomoki Fukuyama of the Azabu University School of Veterinary Medicine and Euglena Co., Ltd. have confirmed research results showing that ingesting Yaeyama Chlorella reduces skin allergy symptoms aggravated by deoxynivalenol (a mold toxin).
Mycotoxin contamination of food has been reported to be a health hazard to humans and livestock. The immunosuppressive effect of deoxynivalenol, a type of mycotoxin, and the weakening of the intestinal barrier due to damage to the digestive system may cause inflammation and allergies. It has also been pointed out that exposure to deoxynivalenol may worsen allergic symptoms in people who already have allergies.
Previous studies have reported that ingestion of Yaeyama Chlorella (a Chlorella strain collected from Ishigaki Island) inhibits the absorption of mycotoxins by direct adsorption of mycotoxins and promotes their excretion. In this study, we used mice with an allergic dermatitis model to verify whether ingestion of Yaeyama Chlorella reduces skin allergy symptoms aggravated by deoxynivalenol.
As a result, compared to the control group, the deoxynivalenol-treated group showed a significant increase in ear skin thickness, itching behavior, and the degree of skin hyperplasia and inflammation evaluated histologically, and allergic dermatitis developed.However, the deoxynivalenol + Yaeyama Chlorella-treated group showed a significant decrease in ear skin thickness, the number of itching behaviors, and the degree of skin hyperplasia and inflammation evaluated histologically, confirming a reduction in allergic dermatitis symptoms.
These results suggest that Yaeyama Chlorella may adsorb deoxynivalenol, thereby suppressing its absorption in the body and preventing the exacerbation of allergic dermatitis.
