The research group of Professor Takuya Matsumoto of Okayama University, in collaboration with Showa University, Osaka University, and Yanagishita Giken Co., Ltd., has developed the world's first adhesive material for biological soft tissues based on metallic titanium.It has been found that by surface-treating titanium, which is a medical metal material, it instantly adheres to biological soft tissues such as dermis and fascia.

 Polymer sutures are commonly used for implantable sensors and medical devices to be immobilized in vivo and for joining biological tissues together in surgical procedures.On the other hand, in the medical field, there has been a strong desire to develop an adhesive for living tissues that can be used easily and quickly for these purposes.

 The research group has begun to develop a new metal adhesive that has both biocompatibility and high adhesive strength by chemically treating the surface of titanium and enhancing the interaction with organic substances such as proteins contained in living tissues.The developed titanium adhesive can be instantly adhered to the soft tissue by lightly pressing it.In addition, the adhesive strength was more than three times stronger than that of the conventional fibrin-based adhesive.

 According to Professor Matsumoto, although this material looks like a thin film of metal, it is gently placed on the soft tissues of the body (especially the dermis and fascia), and it adheres immediately by pressing it with a ton ton, such as hands. It doesn't stick to the epidermis.

 The material developed this time is easy to handle such as sterilization, and can be an excellent adhesive that exerts strong adhesive force in a short time.It is also expected to be applied to implantable sensors and medical devices for internal fixation, and for simple surgical procedures such as tissue joining and tissue deformation correction.

Paper information:[Advanced Materials Interfaces] Titanium as an instant adhesive for biological soft tissue

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