"Yoshida sarcoma" is mentioned in the "Important Science and Technology History Material (nickname: Future Technology Heritage)" released by the National Museum of Nature and Science in the 2nd year of Reiwa, along with Japan's world-leading single-lens reflex cameras.
Yoshida sarcoma is a type of cancer cell and can be maintained in a suspended state in ascites, which makes it possible to study cancer on a cell-by-cell basis and is used for the creation of Japan's first anticancer drug. It had a great influence on the development of. In 1932, Dr. Tomizo Yoshida discovered that the world's first oral administration of a chemical substance caused cancer in the liver of a rat, and in 1943 succeeded in creating cancer cells floating in the ascites of the rat.We also found that cancer cells could be transplanted by injecting into the abdominal cavity of another rat.This is Yoshida sarcoma, which is an important achievement in introducing cell biology into anticancer drug research for the first time in the world.
The future technology heritage includes "Science and technology history materials that show important achievements in the history of science and technology development and have important significance for passing on to the next generation" and "People's lives, economy, society, and culture." "History of science and technology materials that have had a significant impact on Japan" is selected.Yoshida sarcoma was also evaluated for its contribution to cancer research, and was registered this time in order to preserve and utilize it as a valuable material for showing the development of science and technology in Japan.
Since its discovery, Yoshida sarcoma has been repeatedly transplanted and cultured, and while it is stored frozen, it is held at the Cell Bank of the Medical Cell Resources Center of the Institute of Aging Medicine, Tohoku University, where Dr. Yoshida was assigned, and is still used for anticancer drug research. The sale to researchers is continuing.
