The research group of Professor Naoyuki Fuse of the Graduate School of Life Sciences and Professor Kiyokazu Agata of the Graduate School of Science of Kyoto University conducted genome analysis of dark flies and succeeded in narrowing down the genome sequences related to environmental adaptation.We are approaching the mechanism of environmental adaptation.This is the result of joint research with the National Institute of Genetics.
This time, we have succeeded a mixed population of dark flies and wild-type flies in the light and dark places.It was expected that repeated passages would mix both genomes and increase the frequency of SNPs involved in dark adaptation in the dark population.When the frequency change of dark fly SNP was examined by genome analysis, about 6% of the genomic sequences were selected in the dark, and 84 genes were identified as candidate genes involved in dark adaptation.It contained genes related to the sense of smell and circadian rhythm.
In addition to the results of listing candidate genes involved in environmental adaptation of "dark flies", an experimental example of narrowing down the genomic sequences involved in environmental adaptation by subculturing mixed populations in different environments was shown for research on environmental adaptation. Proposed a new methodology.In the future, we would like to identify adaptive genes by integrating the results of dark fly gene expression analysis and genome analysis, and to verify the effects of dark fly SNPs by introducing dark fly SNPs into the wild-type fly genome. ... apparently ...