Professor Yasushi Ishihama and his colleagues at the Graduate School of Pharmaceutical Sciences, Kyoto University have developed the proteome integrated database jPOST and released it to the world.This database is developed by an all-Japan system centered on Kyoto University, including Kumamoto University, Kyushu University, Niigata University, Information and Systems Research Organization, and Science and Technology Promotion Organization (JST).
Proteome means "all expressed proteins" and is a group of molecules that "directly bears vital activities", so it has attracted a great deal of attention mainly in the field of drug discovery, and various large-scale international studies have been conducted. ..Proteome data is accumulated in various places mainly in Europe and the United States in the form of a database, and international cooperation is progressing, but until now, there is no similar database in Japan, and domestic data must be registered in overseas databases. He said he didn't get it.
The jPOST data repository system developed this time (repository is a centralized storage of data) is a standardization, integration, and centralized management of various proteome data scattered in Japan and overseas.This system builds the world's first cross-sectional proteome integrated database with information on various species (humans, animals, plants, yeasts, bacteria, etc.), post-translational modifications (phosphorylation, etc.) and absolute expression levels. It is said that it is.
jPOST is the first international standard proteome data repository in the Asia-Oceania region, and at the 2016 International Human Proteome Organization / Proteometics Standardization Initiative Conference (Belgium), the ProteomeXchange Consortium (PXC), which provides an international standard data repository system, Membership was declared.In the future, it will be possible to collect proteome data from around the world, mainly in Asia, to jPOST.
