A research team from Kinki University and Kaminomoto Honpo Co., Ltd. discovered that the extract of the crude drug "Enmeisou" has the effect of activating dermal papilla cells.
Although alopecia is not a life-threatening disease, it greatly affects the appearance and has a great impact on the quality of life for both men and women, as well as stress, malnutrition, hormonal imbalance, and aging. Since various causes such as these can be considered, the development of a new therapeutic agent that can improve the symptoms of hair loss regardless of the cause is desired.On the other hand, Enmeisou is a crude drug derived from the active ingredient that has been blended in the long-selling hair restorer of Kaminomoto Honpo for 55 years, and refers to "Hikiokoshi", a perennial plant of the Labiatae family.
This time, the research team added and cultured the extract of prolonging life grass to "hair papilla cells", which is a control tower that regulates hair growth, and measured the growth rate. As a result, the growth of hair papilla cells was promoted. It is said that it was discovered.Among them, we succeeded in identifying that the compounds enmein, isodocarpin, nodosin, and oridonin contained in the life-prolonging grass are components that promote the proliferation of dermal papilla cells. ..
Furthermore, enmein, a major component, is one of the growth factors that activates one of the signals that act as a cell proliferation switch when administered to hair papilla cells, promotes hair growth, and prolongs the growth phase of the hair cycle. The effect of enhancing the production of "vascular endothelial growth factor" was also confirmed.
This result is expected to lead to the development of a hair restorer that is effective against thinning hair caused by various causes, regardless of whether it is male or female.
