Jun Takada, graduate student of Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Megumi Arimoto Saga, former associate professor of Okayama University, and Katsuyuki Kiura, former professor of Okayama University Hospital in a mouse experiment by et al.
According to Okayama University, the research group gave mice a kneaded diet containing alcohol-free beer or non-alcoholic beer, then administered a lung carcinogen, and then gave the mice no alcohol-free beer or non-alcoholic beer. and tumor incidence were compared.
As a result, in the experiment with non-alcoholic beer, the average number of lung cancers was 5.5 in mice given only water and food made with water, but with the addition of non-alcoholic beer, the average number of lung cancers increased to 1.7-3.0. decreased.
In experiments with de-alcoholic beer, 93.3% of mice given no beer developed lung cancer, whereas 53.4% of mice given de-alcoholic beer did not develop lung cancer.
An analysis by the research group found that the DNA damage repair promoting action of beer and non-alcoholic beer prevents the onset of cancer.Furthermore, it is believed that the growth of cancer cells is suppressed by inhibiting growth signal transduction.
Paper information:[Genes and Environment] Chemo-preventive effects and antitumorigenic mechanisms of beer and nonalcoholic beertoward 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced lung tumorigenesis in A/J mice