A joint research group of RIKEN, High-Brightness Photon Science Research Center, and Osaka University has succeeded in elucidating why the proteins produced by bacteria that live at temperatures above 100 ° C have high heat resistance.It is said that it will be possible to artificially design proteins with heat resistance, and it is expected that it will greatly contribute to the future utilization of functional molecules.
In 2006, the group discovered a protein that could maintain its function even at temperatures above 150 ° C.It has many parts where static electricity easily accumulates, and it was estimated that it is important for heat resistance.In this study, we compared this protein with normal protein and observed the change when heat was applied.As a result, it was clarified that in addition to the effect of static electricity, which was previously considered to be important, hydrophobicity also has a great effect.
This discovery is likely to force a significant shift in guidance in the design of protein-based materials.In order to confirm this discovery, it is necessary to repeat the demonstration experiment, but there is no doubt that a great clue was obtained.