Okayama University is conducting a side reaction survey at university-based vaccinations with the aim of providing accurate information to the general public regarding vaccination against new coronavirus infections. The final report summarizes the survey responses of a total of 7 Okayama University faculty members and students (21 for the first time and 9 for the second time) who were vaccinated with the new Corona vaccine from Takeda / Moderna from July 6st to September 7,205th.

 According to the survey, after the second inoculation, pain at the inoculation site appeared in 2% and swelling in 90.0% as a local reaction.Local swelling and redness around 55.3 days after inoculation, which is considered to be a delayed skin reaction (COVID arm), appeared around 7 to 1% after the first inoculation, but was hardly observed after the second inoculation. ..

 また2回目接種では、1回目と比較して全身反応の出現頻度が高く、筋肉痛が64.4%、倦怠感が84.2%、頭痛が74.7%、37.5度以上の発熱は88.0%で出現。発熱の出現頻度は40代以下で90%前後と若い世代で高い傾向にあるが、60代以上でも75.4%に発熱がみられた。

 In addition, females tended to have slightly higher adverse reactions than males (eg, about 2% difference in fever).In addition, there was no tendency for the frequency of adverse reactions to increase due to pregnancy or underlying diseases, and even if there was a history of allergies, there was only a slight increase.Compared to the results of post-inoculation side reaction surveys of the Pfizer vaccine conducted at 5 hospitals in Okayama prefecture, the rate of adverse reactions of the Takeda / Moderna vaccine was high, and even when compared with the younger generation (20s or younger), It was a similar trend.

 Vaccine reaction surveys are also conducted by a research group of the Ministry of Health, Labor and Welfare, but since the subjects are SDF personnel, there are many men and a wide range of age groups.Since the subjects of this survey are half men and women and many young people, it seems that they work in a complementary manner to the findings of the research group of the Ministry of Health, Labor and Welfare.

 Professor Takashi Yorito of the Department of Epidemiology and Hygiene, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University said, "There are side reactions to the vaccine, but most of the symptoms are calm the day after the vaccination and the day after the vaccination. I think the benefits are greater, so I hope you can use it as a reference when considering inoculation and making preparations. "

Reference: [Okayama University] Takeda / Moderna Vaccine Adverse Reaction Survey Final Report-What are the results of the second vaccination for younger generations, half male and half female? (PDF)

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