A research group led by Associate Professor Tsuguhito Ota of the Brain and Liver Interface Medicine Research Center, Kanazawa University Pharmaceutical and Health Research Area, has conducted animal experiments using mice and found that "Sulforaphane" is abundant in "broccoli sprout," which is a sprout of broccoli. It was clarified that it has the effect of suppressing obesity.This research was conducted in collaboration with Kanazawa University and Kagome Co., Ltd.
Sulforaphane has been known to be effective in preventing cancer by increasing the detoxification and antioxidant power of chemical substances taken into the body.Furthermore, in recent years, it has been found that overeating and obesity cause the imbalance between oxidation and reduction, which is involved in the onset of various diseases.However, the effect of sulforaphane on obesity has not been clarified.
In addition to the detoxification and antioxidant effects of sulforaphane, which have already been clarified, the research team said, "The effect of promoting browning of fat cells to increase energy consumption and suppress obesity" and "By using a high-fat diet." There are two new actions, "the action of improving the'obesity type'gut microbiota (so) and suppressing metabolic endotoxemia, which is thought to be involved in the development of lifestyle-related diseases such as diabetes." Was clarified.
The results of this study are expected to improve inflammation of the liver and adipose tissue, or insulin resistance, which makes insulin less effective in the body, and lead to prevention of lifestyle-related diseases.