Professor Koichi Nakayama and Assistant Professor Manabu Ito of Saga University School of Medicine and Cyfuse, a manufacturer of regenerative medicine products, will start clinical research to transplant a cell-made artificial blood vessel made with an independently developed bio 3D printer into a patient.It is said that this is the world's first artificial blood vessel made only from the patient's own cells.
According to Saga University, Professor Nakayama and his colleagues collaborated with Kyoto Prefectural University of Medicine and others to create an artificial blood vessel with a length of 3 cm and an inner diameter of 5 mm from skin cells collected from the bases of the legs of three dialysis patients due to renal failure. Made with a bio 5D printer.This artificial blood vessel will be transplanted from the patient's own elbow to the arteriovenous of the forearm as early as this year.
Since it is made only from the cells of the patient, it is expected to reduce the risk of bacterial infection and reduce the pain of patients due to troubles compared to artificial blood vessels made of resin or synthetic fibers.
Dialysis is a treatment method in which blood is taken out of the body of a patient with impaired renal function and the waste products in the blood are filtered.Since the patient drains a large amount of blood from the body, a shunt is provided as a shunt for blood vessels, which is made of the patient's own blood vessels or resin. In addition, there are defects that are easily blocked.
The clinical study plan was approved by an external review board and accepted by the Ministry of Health, Labor and Welfare.After transplantation, observe the condition of the artificial blood vessel for about half a year and confirm the effect.
