Japan IDDM Network, a certified NPO that supports type 1 diabetic patients and their families, provided a research fund of 1 million yen for the research "Cure treatment of type 100 diabetes with mite insect body antigen" by Professor Kazuichi Nakamura of Kitasato University. bottom.In this way, the Japan IDDM Network signed a contract with Juntendo University for the first time in Japan to create a circulation of research funds centered on patients and their families, and this time following Tokushima University and Nagoya University. Is the 4th case.
Type 1 diabetes is of unknown cause and suddenly develops in a wide range of ages from childhood to adulthood, and at current medical standards, it will die within a few days without 4-5 daily injections or pumped insulin supplementation throughout life. It is said to be an intractable disease.Compared to type 2 diabetes, which accounts for the majority of diabetic patients, the number of patients in Japan is about 10 to 14, and the annual incidence rate is 10 to 1.5 per 2.5, which is a rare disease, so the mentality of patients and their families. , The financial burden is large.
In "Cure treatment of type 1 diabetes with tick insect antigen", which is the research subject of Professor Kazuichi Nakamura of Kitasato University Faculty of Veterinary Medicine, we focus on the mechanism of autoimmunity (runaway immune response) that is the etiology of type 1 diabetes. .. When NOD / ShiJcl mice, which are model animals that spontaneously develop type 1 diabetes, are administered with an extract from mite worms (KVT-1), lymphocyte infiltration (isletitis) into the pancreatic islets, which is characteristic of type 1 diabetes, occurs. Found to be suppressed.In this study, we will narrow down the part of the extract from the mite body that shows the medicinal effect, and try to realize a therapeutic drug for type 1 diabetes.
The Japan IDDM Network established the Type 1 Diabetes Research Fund in 2005 with the aim of changing from a disease that does not cure type 1 diabetes to a disease that "cures" and eventually eradicates (= treatment + eradication + prevention).With support from all over Japan, such as direct donations and "Japan IDDM Network designation" hometown tax payments to the Saga Prefectural Government, 84 research grants of 4 million yen have been subsidized so far.
