Through joint research between Nagoya University and Alberta University in Canada, Aichi Medical University, Kobe University, Hamamatsu University School of Medicine, etc., it is newly revealed that the family environment at an early age and individual oxytocin receptor gene polymorphisms affect "trust". all right.

 It is known that "trust" is difficult to develop when growing up in a family environment with a low socioeconomic status.On the other hand, it is thought that the difference in the base sequence (gene polymorphism) of the gene encoding the receptor of the peptide hormone "oxytocin", which is said to promote interpersonal communication, may also affect the reliability.However, previous studies have not examined how family environment and genetic individual differences other than socioeconomic status and their interactions affect trust.

 Therefore, in this study, we will compare and culturally examine the relationship between the family environment evaluated by indicators such as how to treat parents and the degree of order in the family, and the individual differences and trust of oxytocin receptor gene polymorphisms with Japan. I conducted a study on students in Canada.As a result, those who answered that they grew up in a stressful family environment such as lack of affection and abuse from their parents had lower trust in others.And importantly, this relationship was influenced by oxytocin receptor gene polymorphisms.Regardless of whether they were Japanese or Canadian, those who had the oxytocin receptor gene AA had a lower degree of trust than those who had problems with their childhood home environment, but those who had the oxytocin receptor genes AG and GG had less confidence. , It is said that such a relationship was not recognized.

 The results of this study are the first findings that clearly show that it is necessary to consider both environmental and genetic individual differences in fostering trust.It can be said to give important suggestions for understanding the factors that contribute to the building of trust, especially in Japan, where trust in others is lower than in North America.

Paper information:[Psychoneuroendocrinology] Oxytocin Receptor Gene (OXTR) and Childhood Adversity Influence Trust

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