The research team of Associate Professor Kei Ito, Researcher Asako Tsubouchi, and Graduate Student Tomoko Yano of the Institute of Molecular and Cellular Biology, University of Tokyo, used Drosophila melanogaster to elucidate the structure of the entire somatic sensory neural circuit of insects for the first time. It was revealed that it is extremely similar to that.

 Of the five senses, the four senses of sight, hearing, smell, and taste are detected by specific sensory organs such as eyes, ears, nose, and mouth.On the other hand, somatosensory (tactile sensation) has a complicated structure in which various sensory organs scattered throughout the body send information to the brain, and the whole picture is unclear.

 The research team created a genetically modified system that can induce gene expression in only some types of cells using Drosophila melanogaster.By screening this, we succeeded in specifically manipulating all types of somatosensory cells and analyzing nerve fibers extending to the central nervous system.Thus, experiments in which activity is detected and functions are manipulated by only one specific type of nerve in the sensory nervous system are extremely difficult in mammalian experimental animals.

 It was found that the neural circuit revealed this time has a very high similarity to mammals.It is already known that the neural circuit structures of sight, smell, and taste are very similar between insects and mammals.In addition, the team found in a few years ago that the central structures that detect sound and gravity are similar in insects and mammals.This study of somatosensory has found commonality in the neural circuit structures of all five senses.

 It is concluded that this did not mean that the brains of insects and us mammals evolved apart, but that there was a common ancestor with a brain with these five senses, and that it was more likely that they evolved separately. ..

Paper information:[Science] Topological and Modality-specific Representation of Somatosensory Information in the Fly Brain

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The University of Tokyo was established in 1877 (Meiji 10) by integrating the Tokyo Kaisei School and the Tokyo Medical School.Since its establishment, it has developed education and research in a unique way in the world as a leading university in Japan and an academic center for the fusion of East and West cultures.As a result, many human resources have been produced in a wide range of fields, and many research achievements […]

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