A research team led by Dr. Koichi Miyashita at Hamamatsu University School of Medicine analyzed large-scale data on adult patients with the new coronavirus infection (COVID-19), and found that during the delta strain epidemic, patients became younger and the mortality rate (especially 65 years old) increased. (above) showed a significant decline.However, the risk of death may increase or fluctuate depending on comorbidities.

 COVID-2019, which has spread all over the world since 19, is still a major social problem.The situation is changing dramatically due to viral mutation, vaccine spread, treatment development, and policies. An investigation was called for.

 『レセプト情報・特定健診等情報データベース(NDB)』はパンデミック初期からデルタ株流行期までのCOVID-19患者約94万人のビックデータだ。このデータから研究グループは患者の診断時期を従来株流行期(2020/1/1~2021/4/18)、アルファ株流行期(2021/4/19~7/18)、デルタ株流行期(2021/7/19~8/31)に分け、患者の臨床像や死亡率、死亡リスク因子の推移を解析した。

 As a result, COVID-19 patients during the delta epidemic became younger and had a significantly lower mortality rate (2.9% during the conventional epidemic, 2.2% during the alpha epidemic, and 0.4% during the delta epidemic). epidemic season 65%).The decline in mortality was particularly pronounced among those aged XNUMX and over.Patients with comorbidities such as advanced age, male sex, malignant tumors, renal disease, congestive heart failure, chronic obstructive pulmonary disease, hemiplegia, and metastatic solid tumors were at higher risk of death in all epidemics, but liver For some comorbidities, such as disease, the risk fluctuated according to the epidemic.

 In addition to understanding the epidemiology of COVID-19, the results of this research are expected to be used for administrative measures.Furthermore, the research method used can be used for large-scale epidemiological surveys in new epidemics after the Omicron strain. and

Paper information:[Emerging Microbes & Infections] Changes in the Characteristics and Outcomes of COVID-19 Patients from the Early Pandemic to the Delta Variant Epidemic: A Nationwide Population-based Study

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