A joint research group consisting of RIKEN, Keio University, Tokyo Metropolitan University, and the Exploratory Research Center for Advanced Life Sciences has developed and released a digital brain database of the common marmoset, a small primate, using magnetic resonance imaging (MRI). .
The common marmoset, a small primate, has a brain structure similar to that of humans and a relatively short lifespan, so it is used in brain science research and aging research.Previously, a publicly available magnetic resonance imaging (MRI) database of common marmoset brains focused on the age of development and maturity (approximately 2 years), but included senescence that occurs after 7-8 years of age. There was no database for the ~1 year age group.The research group aimed to acquire a multi-contrast MRI brain database of the common marmoset brain (images that can measure various biological information) that covers a wide range of age groups, genders, and physiques.
This time, the joint research group measured and analyzed the brains of 216 healthy common marmosets (88 males, 128 females, 0.8 to 10.3 years old), and obtained results that are effective for preclinical research in brain science. A digital brain MRI database was released.From the database, it is possible to download only the necessary information and check the brain images of each individual, providing highly reliable detailed brain structure and function data and their connection information, as well as essential information on the effects of aging on the brain. offer.
This multi-contrast MRI database contains a wide range of information such as age, gender, and build (weight), and is currently the world's largest public database of common marmoset brains.It is expected to help us understand the effects of factors such as age, gender, and physique on the brain.It is also expected to contribute to the development of the brain science community around the world as open science and accelerate research.
Paper information:[Scientific Data] Multi-modal brain magnetic resonance imaging database covering marmosets with a wide age range