Yokohama City University will develop a system that enables "quantitative" and "large-scale" measurement for the purpose of detecting new coronavirus antibodies, and will start research for prompt introduction into society.

 In March 2020, a research group led by Professor Akihide Liang of Yokohama City University succeeded in detecting antiviral antibody (IgG) contained in the serum of patients suffering from a new coronavirus infection, and a diagnostic method. And the development of reagent kits.

 This time, using this antibody detection technology, Yokohama City University, Tosoh Corporation, and Kanto Chemical Co., Inc. will collaborate to develop a system that can measure new coronavirus antibodies "quantitatively" and "on a large scale."Specifically, (XNUMX) development of research reagents and systems that can detect with high sensitivity and specificity (high performance), (XNUMX) realization of high test efficiency and large-scale measurement (throughput), and (XNUMX) antibody detection method through measurement of clinical specimens. The pillar is the practical application of. We aim to seamlessly implement the three issues and promptly introduce the developed measurement system into society.If the possibility of social implementation of the system is shown, it is expected that in the future, epidemiological research will be carried out and technological innovation will be prepared for a pandemic.

 At present, the clinical significance, reliability knowledge, and scientific basis for new test methods for new coronaviruses, especially antibody tests, are still insufficient.In order to maximize the advantages of the test method to be developed and to make it useful in clinical practice, we will scientifically verify the properties and characteristics of the antibody test method, and have a solid understanding of changes in test results and their interpretation over time after infection. Is extremely important, and it is said that these problems will be clarified and the way of thinking about the evaluation method will be organized.

reference:[Yokohama City University] "Development of high-throughput fully automatic immunoassay method for detection of new coronavirus antibody and research for social implementation of the measurement method" by the subsidy project of Japan Agency for Medical Research and Development (AMED) start

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