List of articles on drug discovery

Elucidation of structure of Escherichia coli "respiratory enzyme", revealing diversity Kyushu Institute of Technology

 Professor Junji Sakamoto of Kyushu Institute of Technology and colleagues have elucidated the precise three-dimensional structure of "cytochrome bd-type respiratory enzyme" that works in Escherichia coli.

Succeeded in developing the world's first artificial cell microcapsule using DNA origami

 A research group led by Associate Professor Masahiro Takinoue of Tokyo Institute of Technology imitated cell membranes with DNA nanoplates made from DNA origami, […]

Launch of cells for drug discovery support derived from human iPS cells Nagoya City University and Fujifilm

 The result of joint research between Professor Tamhide Matsunaga of Nagoya City University and FUJIFILM Corporation, which is the most suitable human iPS cell for evaluation of drug absorbability […]

Kyoto University discovers an enzyme that works to develop dermatitis to develop a new drug to replace steroids

 A research group at Kyoto University has found that suppressing the action of an enzyme called p38-MAP kinase will lead to the development of new external drugs […].

Succeeded in innovative cost reduction of peptides for full-scale commercialization of medium-molecular-weight drugs Chubu University

 A group of Professor Hisashi Yamamoto and his colleagues at Chubu University succeeded in developing a new and efficient method for synthesizing peptides (protein fragments), and used peptides for the skeleton […].

DNA damage caused by ultraviolet rays becomes easier to access by "sliding" Kobe University, etc.

 Professor Kaoru Sugazawa of Kobe University Biosignal Research Center, Professor Hitoshi Kurumizaka of Institute of Quantitative Life Sciences, University of Tokyo, Shigeru Iwai of Graduate School of Osaka University […]

Gifu University succeeded in making sialic acid with only α bond for the first time

 A research group at Gifu University has realized the stereoselective binding reaction of sialic acid, which has been a difficult problem for 50 years.

Developed by Waseda University, a metal nano-processed puncture thin film that delivers substances into cells quickly and safely

 Research groups at Waseda University and the University of Kitakyushu have developed a metal nano-processed puncture thin film using microfabrication technology and inserted it into cells […].

Peptide barcode method for producing antibodies without using animals Kyoto University

 A research group at Kyoto University has produced monoclonal antibodies (antibodies with one antigen-determining site) in vitro and can quickly and easily screen […]

Treatment of systemic cancer with injectable drug Osaka University develops injection solution that emits alpha rays

 A research group at Osaka University has succeeded in producing a therapeutic drug that emits alpha rays, which are highly effective in treating cancer.
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