A research group led by Professor Yojiro Anzai of the Department of Microbiology, Faculty of Pharmaceutical Sciences, Toho University announced that he has discovered a new species of the rare actinomycete Actinocatenispora.
Actinomycetes are bacteria that produce various substances that are widely distributed in nature, such as soil and plants, and include pharmaceuticals such as antibiotics that are indispensable for current medical treatment.Professor Anzai and his colleagues are working with a research group led by Professor Javzan Batkhuu of Mongolian National University, which has an academic exchange agreement, to search for useful substances using actinomycetes. It is said that an actinomycete isolation experiment was conducted on the medicinal plant Comarum salesowianum, which is known to have.
The strain NUM-2625 isolated from Comarum salesowianum was strongly suggested to be a species of the rare actinomycete Actinocatenispora as a result of genetic analysis.Therefore, as a result of comparing the genomic sequences of NUM-2625 and existing bacterial species of the genus Actinocatenispora with Dr. Tomohiko Tamura of the Biotechnology Center of the Product Evaluation Technology Infrastructure Organization, NUM-2625 is the existing bacterial species of the genus Actinocatenispora. It became clear that it was a different new species. There are three existing species of the genus Actinocatenispora, all of which are said to have been isolated from soil, and NUM-3 was the first actinomycete of the genus Actinocatenispora to be isolated from plants.
Although the production of useful substances has not been confirmed from this strain named Actinocatenispora comari NUM-2625T, a new species of actinomycete, which is a producer of pharmaceuticals such as antibacterial drugs, antineoplastic drugs, and immunosuppressive drugs, is , Expectations for new drug development are high.In particular, the discovery from Mongolia, where there are few reports of new species discovery, is expected to lead to research on biodiversity and exploratory research on new useful substances.
