Tabata training is a type of interval training that involves 50 seconds of high-intensity exercise and 20 seconds of rest, which can lead to exhaustion in about 10 seconds in a row, for a total of 1 to 6 sets, which is about 7 minutes. An extremely high exercise effect can be obtained in a short time.It is said to have been adopted by the world's top athletes as an efficient training that can simultaneously maximize the aerobic and anaerobic energy supply mechanism.

　It is known that colorectal cancer becomes an adenoma (polyp) via aberrantcrypt foci (ACF), which is considered to be the early stage of cancer (precancerous cells), before it changes from normal epithelial cells to carcinoma. Has been done.

This time, when this training was performed on rats fed with carcinogens by swimming, it was revealed that the number of ACF in colon endothelial cells was less than half that in the non-trained group.
This result shows that Tabata training has the effect of suppressing the onset of colorectal cancer, in addition to moderate exercise that is generally considered to be effective in preventing cancer from the viewpoint of "stress" and "immunity". It is said that it suggests.

In addition, a tabata training experiment in humans increased human blood SPARC levels to the same extent as 30 minutes of moderate exercise, and a tabata training experiment in 11 healthy young men showed human skeletal muscle. It was clarified that the SPARC mRNA of the above was increased.
SPARC (Secreted Protein Acidic and Rich in Cysteine) is one of the proteins secreted from skeletal muscle by exercise and is known to induce apoptosis (cell death) of ACF in the large intestine.
This suggests that Tabata training and high-intensity exercise may be effective for primary prevention of colorectal cancer.

Paper information: [Medicine and Science in Sports and Exercise] A mechanism underlying preventive effect of high intensity training on colon cancer