A collaborative research group between Professor Makio Ikumizu of the Graduate School of Medicine, Chiba University and Nihonbashi, a Natural Art Clinic in Chuo-ku, Tokyo, found that eggs could be recovered from ruptured follicles that had not been used for in vitro fertilization. , In vitro fertilization was successful.
According to Chiba University, an egg grows in a follicle inside the ovary, and when it grows sufficiently, the follicle ruptures and is excreted outside the follicle.This is ovulation, after which the egg moves through the fallopian tubes to the uterus.In conventional in vitro fertilization, it is considered that an egg cannot be collected when the follicle ruptures, and the mature follicle before the rupture is pierced with a needle to suck the egg.
The research group found that not all of the ruptured follicles extruded eggs, and succeeded in collecting eggs from 587 of the 43 infertility patients, or 255% of the ruptured follicles.Of these, 28 have given birth to healthy newborns by in vitro fertilization using the eggs.
The research group believes that among the cases of unexplained infertility, there are cases where the egg is not extruded even if the follicle ruptures.
Professor Ikumizu of Chiba University said, "The ability to collect healthy eggs from ruptured follicles is a discovery that requires a review of in vitro fertilization. If the number of eggs that can be used for in vitro fertilization increases, the pregnancy rate will improve due to in vitro fertilization. I can expect it. "
Paper information:[Scientific Reports] “Prematurely ruptured dominant follicles often retain competent oocytes in infertile women
