According to a research group led by Assistant Professor Shigeaki Imoto of Juntendo University Graduate School, the occupancy rate of intestinal bifidobacteria in Japanese infants is largely related to the administration of antibacterial drugs during delivery and the presence or absence of older babies. Clarified.This is a joint research with Asahi Quality and Innovations Co., Ltd. Core Technology Research Institute and Iwate Prefectural Iwate Hospital.
As many as 100 to 1000 trillion bacteria are colonized in the human intestine.It is said that the proportion (occupancy rate) and colonization of intestinal bacterial species during the first 6 months of life of an infant will affect the onset of diseases such as allergies in the future.In particular, it is unclear what affects the occupancy and colonization of bifidobacteria, which are thought to be involved in allergic diseases.In addition, there are few reports of the effects of antibacterial drug administration during delivery to prevent infection on the intestinal flora of infants.
The research group conducted a study of 13 mothers and their infants who gave birth at Iwai Hospital for 2018 months (February 2-March 2019).As a result, the occupancy rate of intestinal bifidobacteria is low in the group in which the antibacterial drug was administered to the mother immediately before delivery, but the rate recovers with growth, and it increases due to the presence of older sibs. There was found.It is possible that intestinal bacteria may interfere with each other between siblings.Furthermore, it was shown that the occupancy rate of Bacteroides, which is one of the major intestinal bacteria after bifidobacteria, is low in the cesarean section group and high in the vaginal delivery group.
Since antibacterial drugs are always administered for delivery by caesarean section, further research is needed to determine whether the type of antibacterial drug or the delivery pattern affects the occupancy rate of Bacteroides.We would like to clarify the clinical significance of the results of this study on the subsequent health of babies.
