A research group from the graduate school of Osaka Public University (Yuko Nitahara and other graduate students) and the graduate school of Gunma University conducted an international joint research project with the Ministry of Health of El Salvador and the University of El Salvador, etc., and investigated the high risk of Chagas disease infection through vector insect surveys throughout El Salvador. Identify your region.Efficient countermeasures are expected.

 Chagas disease is prevalent mainly among the world's poor, and the number of infected people worldwide, mainly in Latin America, is estimated to be 600 to 700 million.About 3% of the population in El Salvador, which has many mud-walled houses and is home to many vector insects, is said to be affected.In the early stages of infection, most of them are asymptomatic, and if they develop serious heart disease after becoming chronic, there is no cure and they die. It is one of the "neglected tropical diseases" designated by the WHO, and investigations and studies on the risk of infection by vector insects have been inadequate.

 The research team investigated 2018 houses across El Salvador from September 9 to November 2020, and as a result, collected 11 vector insects (assassin bugs) in 311 houses, observed their droppings under a microscope, Detection of the pathogen (Trypanosoma cruzi) was performed.DNA was extracted from fecal samples that were confirmed to be infected, and a PCR diagnosis was performed.

 The study found a 34% home invasion rate for vector insects and a 10% infection rate for pathogens.Although the pathogen is ubiquitous throughout El Salvador, 14 out of 5 regions (departments) have high prevalence.

 The results of this research will enable continuous and selective vector control, especially in highly infected areas, and are expected to be utilized for efficient allocation of resources for vector control by local governments.In the future, we will further clarify the pathogenesis of Chagas disease and clarify the relationship between the genomic background of the parasite and the onset of the disease.

Paper information:[Infectious Diseases of Poverty] Re-emerging threat of Trypanosoma cruzi vector transmission in El Salvador, update from 2018 to 2020

Gunma University

Pursuing the academic discipline that you have decided on your own, "Run through the group, run the world"

Gunma University was established as a new national university in 24, and has four faculties representing the northern Kanto region (4 majors in the Faculty of Joint Education, Department of Social Informatics in the Faculty of Social Informatics, 13 majors in the Department of Health Sciences, Faculty of Medicine, and 4 in the Faculty of Science and Technology). It is a comprehensive university of the department).A wide range of international […] who can tackle new difficult issues enthusiastically and creatively.

Osaka Public University

In April 2022, "Osaka Public University" was opened by the fusion of Osaka Prefectural University and Osaka City University.

Osaka Metropolitan University was opened in April 2022 by integrating Osaka Prefectural University and Osaka City University.Both are universities with a history of about 4 years, and are general universities with 140 faculties, and the number of students is about 12.It is the largest public university in Japan.A new "base of knowledge" that connects people, society, cities, and the world to the metropolis of Osaka […]

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