In recent years, genome editing technology has been developed that can modify the genome of living organisms accurately and efficiently, and may be applied to medicine.On the other hand, various ethical, legal, and social issues (ELSI) have emerged, and it is necessary to establish appropriate research governance.For this reason, in addition to regulations such as legislation by government agencies, the autonomy of the research community and the role of citizens have attracted attention, but there has been no concrete progress in research on how diverse people (stakeholders) should be involved in governance. rice field.

　This time, the research group focused on the Bioethics Expert Committee established in Japan's Cabinet Office.Discussed research governance of human genome editing (especially research ethics review system) and analyzed the involvement of each stakeholder in the process.As a result, the research community (academic society, etc.) and the patient community (patient association, etc.) are involved in the governance of emerging medical technologies, and new initiatives such as citizen interactive events were confirmed.Also, government agencies and the research community played a role in collaboration with other stakeholders, and citizens engaged in multiple ways in ways that differed from experts.Furthermore, it was suggested that consideration of the role of citizens is important for establishing research governance involving various stakeholders.

　As a result, the roles of the government, experts, citizens, and patients in the governance of advanced medical technology, including human genome editing technology, and the research ethics review system have been clarified.It is expected that it will serve as a guideline for effective practice in countries and organizations that are trying to address the governance of emerging medical technologies with various stakeholders.

Paper information:[Asian Bioethics Review] Stakeholder Involvement in the Governance of Human Genome Editing in Japan