The research group of Professor Kazuhiko Katayama of Kitasato University has an inactivating (disinfecting) effect on the new coronavirus mainly for commercial products (household detergents, hygiene products, etc.) containing ethanol and surfactant components. Whether or not it was evaluated in vitro.

 Information on how to disinfect the new coronavirus is provided on the websites of the Ministry of Health, Labor and Welfare and the National Institute of Infectious Diseases.However, there is little information on the inactivating effect of commercial products (quasi-drugs and miscellaneous goods) that are generally distributed on the market.

 Of the inactivated pharmaceutical products and miscellaneous goods on the market, the new coronavirus is not available for commercial products (22 items) that mainly contain ethanol and surfactant components and are expected to have a disinfecting effect on the new coronavirus. An in vitro virus inactivation evaluation was performed to determine the possibility of having an activation effect.In consideration of the utilization of information, all the names of the products used in the test are disclosed.

 The virus solution was mixed with the test target solution and contacted at room temperature for 1 minute or 10 minutes.Then, the cells were diluted with the medium used for culturing and added so that the mixed solution did not affect the cells used for the test, and the cells were cultured for 6 days.Cytotoxicity was confirmed daily by microscopic observation.The viral load was detected on the 0th, 3rd, and 6th days.The test solution in which no cell damage occurred and no increase in the amount of viral RNA was confirmed was considered to have a virus inactivating effect.

 As a result, it was considered that ethanol can sufficiently inactivate the virus with a contact time of 50 minute at a concentration of 1% or more.Products with confirmed inactivating effects were considered to be effective in inactivating the new coronavirus.In addition to cleaning hands and hard surfaces where there is concern about contamination with the new coronavirus, it can be expected to be used for cleaning clothes and linens used daily.

reference:[Kitasato University] Inactivation effect of new coronavirus (SARS-CoV-2) for quasi-drugs and miscellaneous goods (PDF)

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